Sunday, May 08, 2011

Principles of Allergy Diagnosis

Positive skin tests may not be associated with clinical
symptoms (allergy):


Manifestations of allergy differ with age:


Allergy increases target organ hyperresponsiveness, which
lowers the threshold to subsequent allergen exposure:

Interrelationships between allergy and hyperresponsiveness,
which may have both IgE-mediated and non-IgE-mediated
components. SPT, skin prick test:



therapeutic trial of avoidance of the suspected allergen or
provocation testing in the target organ. These parameters are
discussed and a diagnostic approach is recommended.

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